Skin Allergens

Skin Allergens Database

Welcome to our skin allergens database.  These are substances and ingredients we have found that cause eczema and various contract dermatitis.  These are extracted from personal experiences of our test volunteers and dermatological databases all over the world.  These link to article or page with information on the allergen and references.

Example of contact skin allergen eczema

Ethylene Brassylate

Fusidic Acid

Methylisothiazolinone

Methylchloroisothiazolinone

Cetyl alcohol also known as Hexadecan-1-ol and Palmityl alcohol

Triethanolamine CAS Number 102-71-6

Note: We will be doing write ups on all of these in the future

Established contact allergens in humans EU List of fragrance ingredients

ACETYLCEDRENE   CAS Number  32388-55-9

Cinnamaldehyde  CAS Number 1437-10-9

 
INCI name (or, if none exists, perfuming name according to CosIng) CAS number Human evidence: see text
 Individual chemicals
ACETYLCEDRENE 32388-55-9 +
AMYL CINNAMAL* 122-40-7 ++
AMYL CINNAMYL ALCOHOL* 101-85-9 ++
AMYL SALICYLATE 2050-08-0 +
trans-ANETHOLE 4180-23-8 + (r.t.)
ANISE ALCOHOL* 105-13-5 +
BENZALDEHYDE  100-52-7 +
BENZYL ALCOHOL* 100-51-6 ++
BENZYL BENZOATE* 120-51-4 ++
BENZYL CINNAMATE* 103-41-3 ++
BENZYL SALICYLATE* 118-58-1 ++
BUTYLPHENYL METHYLPROPIONAL * 80-54-6 ++
CAMPHOR 76-22-2 / 464-49-3 + (r.t.)
beta-CARYOPHYLLENE (ox.) 87-44-5 Non-ox.: +, ox.: +
CARVONE 99-49-0 / 6485-40-1 / 2244-16-8 + (r.t.)
 CINNAMAL* 104-55-2 +++
CINNAMYL ALCOHOL* 104-54-1 +++
CITRAL* 5392-40-5 +++
CITRONELLOL* 106-22-9 / 1117-61-9 / 7540-51-4 ++
COUMARIN*  91-64-5 +++
(DAMASCENONE ) ROSE KETONE-4 23696-85-7 + (r.t.)
alpha-DAMASCONE (TMCHB) 43052-87-5 / 23726-94-5 ++
cis-beta-DAMASCONE 23726-92-3 +
delta-DAMASCONE 57378-68-4 +
DIMETHYLBENZYL CARBINYL ACETATE (DMBCA) 151-05-3 +
EUGENOL* 97-53-0 +++
FARNESOL* 4602-84-0 ++ – +++
GERANIOL 106-24-1 +++
HEXADECANOLACTONE 109-29-5 + (r.t.)
HEXAMETHYLINDANOPYRAN 1222-05-5 ++
HEXYL CINNAMAL* 101-86-0 ++
HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE (HICC)* 31906-04-4 / 51414-25-6 ++++
HYDROXYCITRONELLAL* 107-75-5 +++
ISOEUGENOL* 97-54-1 +++
alpha-ISOMETHYL IONONE* 127-51-5 ++
(DL)-LIMONENE 138-86-3 ++ (non-ox.); +++ (ox.)
LINALOOL 78-70-6 ++ (non-ox.) +++ (ox.)
LINALYL ACETATE 115-95-7 + (non-ox.) ++ (ox.)
MENTHOL 1490-04-6 / 89-78-1 / 2216-51-5 ++
6-METHYL COUMARIN 92-48-8 ++
METHYL 2-OCTYNOATE* 111-12-6 ++
METHYL SALICYLATE 119-36-8 +
3-METHYL-5-(2,2,3-TRIMETHYL-3-  67801-20-1 ++ (r.t.)
CYCLOPENTENYL)PENT-4-EN-2-OL    
alpha-PINENE and beta-PINENE 80-56-8 and 127-91-3, resp. ++
PROPYLIDENE PHTHALIDE 17369-59-4 + (r.t.)
SALICYLALDEHYDE 90-02-8 ++
alpha-SANTALOL and beta-SANTALOL 115-71-9 and 77-42-9, resp. ++
SCLAREOL 515-03-7 +
TERPINEOL (mixture of isomers) 8000-41-7 +
alpha-TERPINEOL  10482-56-1 / 98-55-5
Terpinolene 586-62-9 +
TETRAMETHYL ACETYLOCTAHYDRONAPHTHALENES 54464-57-2 / 54464-59-4 / 68155-66-8 / 68155-67-9 +
TRIMETHYL-BENZENEPROPANOL (Majantol) 103694-68-4 ++
VANILLIN 121-33-5 ++
 Natural extracts
CANANGA ODORATA and Ylang-ylang oil    83863-30-3; 8006-81-3 +++
CEDRUS ATLANTICA BARK OIL  92201-55-3; 8000-27-9 ++
CINNAMOMUM CASSIA LEAF OIL CINNAMOMUM ZEYLANICUM BARK OIL 8007-80-5 84649-98-9 ++ (r.t.)
CITRUS AURANTIUM AMARA FLOWER / PEEL OIL 8016-38-4; 72968-50-4 ++
CITRUS BERGAMIA PEEL OIL EXPRESSED 89957-91-5 + (r.t.)
CITRUS LIMONUM PEEL OIL EXPRESSED 84929-31-7 ++
CITRUS SINENSIS (syn.: AURANTIUM DULCIS) PEEL OIL EXPRESSED 97766-30-8; 8028-48-6 ++
CYMBOPOGON CITRATUS / SCHOENANTHUS OILS 89998-14-1; 8007-02-1; 89998-16-3 ++
EUCALYPTUS SPP. LEAF OIL 92502-70-0; 8000-48-4 ++
EUGENIA CARYOPHYLLUS LEAF / FLOWER OIL 8000-34-8 +++
EVERNIA FURFURACEA EXTRACT* 90028-67-4  +++
EVERNIA PRUNASTRI EXTRACT* 90028-68-5  +++
JASMINUM GRANDIFLORUM / OFFICINALE 84776-64-7; 90045-94-6; 8022-96-6 +++
JUNIPERUS VIRGINIANA 8000-27-9; ++
  85085-41-2  
LAURUS NOBILIS 8002-41-3; 8007-48-5; 84603-73-6 ++
LAVANDULA HYBRIDA 91722-69-9 + (r.t.)
LAVANDULA OFFICINALIS 84776-65-8 ++
MENTHA PIPERITA 8006-90-4; 84082-70-2 ++
MENTHA SPICATA 84696-51-5 ++
MYROXYLON PEREIRAE 8007-00-9; ++++
NARCISSUS SPP. diverse ++
PELARGONIUM GRAVEOLENS 90082-51-2; 8000-46-2 ++
PINUS MUGO/PUMILA 90082-72-7 / 97676-05-6 ++
POGOSTEMON CABLIN 8014-09-3; 84238-39-1 ++
ROSE FLOWER OIL (ROSA SPP.) Diverse ++
SANTALUM ALBUM 84787-70-2; 8006-87-9 +++
TURPENTINE (oil) 8006-64-2; 9005-90-7; 8052-14-0 ++++
VERBENA ABSOLUTE 8024-12-2 ++